Scientist Antibody Discovery

Scientist Antibody Discovery needs significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques

Scientist Antibody Discovery requires:

• PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+ years of research experience, BS with 10+ years of research experience in antibody or protein engineering

• Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins

• Demonstrated experience in working collaboratively across various scientific disciplines and other parts of the organization to meet end goals

• Highly motivated individual with exceptionally good organizational skills, and attention to details •

• Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design

• Experience in NGS analysis for antibody discovery and engineering

• Significant contributions to successful biologics drug discovery programs in biotech/biopharma industry

Scientist Antibody Discovery duties:

• Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display

• Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits

• Rank-order clones by affinity, in vitro potency, and early developability assessment

• Execute sequence optimization of lead antibodies to improve developability and binding affinity